Topamax was the one that made me insane. Hopefully you won't be one of the people for whom it increases anxiety, depression, mood swings, and general hysteria -- or any of the other more "just a nuisance" type side effects: http://www.relieve-migraine-headache.com/topamax-side-effects.html I really, REALLY hope it works well for you. Especially because it does make you lose weight. (Everybody loves that side effect! If I hadn't gone batshit crazy on that drug, I would have kept taking it just because it made me drop nearly 30lbs without even trying!)